, vol. 282, issue 18, pp. 13316–13325, May 4, 2007.
>‹‹528›› Effect of dietary trans fatty acids on the delta 5, delta 6 and delta 9 desaturases of rat liver microsomes in vivo, Mahfouz M, Acta Biol Med Ger, 1981, 40(12):1699–1705. Это исследование показывает, что пищевые трансжирные кислоты дифференцированно встраиваются в микросомные липиды печени и работают как ингибиторы дельта-9 и дельта-6 десатураз. Дельта-6-десатураза считается ключевым ферментом, перерабатывающим незаменимые жирные кислоты в арахидоновую кислоту и простагландины. Это показывает, что присутствие трансжирных кислот в рационе может в определенной степени влиять на метаболизм незаменимых жирных кислот, мешая работе десатураз.
>‹‹529›› A defect in the activity of delta 6 and delta 5 desaturases may be a factor predisposing to the development of insulin resistance syndrome, Das UN, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 72, issue 5, May 2005, pp. 343–350.
>‹‹530›› Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol, M Ntambi, September 1999, Journal of Lipid Research, 40, pp. 1549–1558.
>‹‹531›› Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome, H E Popeijus, International Journal of Obesity, 32, 1076–1082, doi 10.1038/ijo.2008.55, published online April 22, 2008.
>‹‹532›› Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells, Mantzaris, February 2011, 278(3):519–30, doi 10.1111/j. 1742–4658.2010.07972.x.
>‹‹533›› The significance of differences in fatty acid metabolism between obese and non-obese patients with non-alcoholic fatty liver disease, Nakamuta M, Int J Mol Med, November 2008, 22(5):663–7.
>‹‹534›› Liver mitochondrial dysfunction and oxidative stress in the pathogenesis of experimental nonalcoholic fatty liver disease, Oliveira CP, Braz J Med Biol Res, February 2006, 39(2): 189–94, epub February 2006.
>‹‹535›› Insulin resistance, inflammation, and non-alcoholic fatty liver disease, Tilg H, Trends Endocrinol Metab, October 15, 2008, epub prior to print.
>‹‹536›› Apoptosis in skeletal muscle myotubes is induced by ceramide and is positively related to insulin resistance, Turpin SM, Am J Physiol Endocrinol Metab, 291: El341-El350, 2006.
>‹‹537›› Weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome (review), Unger RH, Endocrinology, December 2003, 144(12):5159–65.
>‹‹538››Prostaglandins, Chuck S. Bronson, Nova Publishers, 2006. p. 51.