152 «Мышь буквально превращается в марионетку»: Aponte, Atasoy, and Sternson, “AGRP neurons Are Suffi cient; Betley, Xu, Cao, Gong, Magnus, Yu, et al., “Neurons for Hunger and Thirst; Wu, Whiddon, and Palmiter, Ablation of Neurons; M. E. Carter, M. E. Soden, L. S. Zweifel, and R. D. Palmiter, Genetic Identification of a Neural Cir cuit That Suppresses Appetite, Nature 503, no. 7474 (November 7, 2013): 111–14; B. P. Shah, L. Vong, D. P. Olson, S. Koda, M. J. Krashes, C. Ye, et al., “MC4R- Expressing Glutamatergic Neurons in the Paraventricular Hypothalamus Regulate Feeding and Are Synaptically Connected to the Parabrachial Nucleus, Proceedings of the National Acad emy of Sciences of the United States of America 111, no. 36 (September 9, 2014): 13193–98.
152 «бесчисленное множество операций»: F. A. C. Azevedo, L. R. B. Carvalho, L. T. Grinberg, J. M. Farfel, R. E. L. Ferretti, and R. E. P. Leite, et al., Equal Numbers of Neuronal and Nonneuronal Cells Make the Human Brain an Isometrically Scaled- Up Primate Brain, Journal of Comparative Neurology 513, no. 5 (April 10, 2009): 532–41.
153 «происходят в мозге человека»: C. T. De Souza, E. P. Araujo, S. Bordin, R. Ashimine, R. L. Zollner, A. C. Boschero, et al., Consumption of a Fat- Rich Diet Activates a Proinfl ammatory Response and Induces Insulin Re sis tance in the Hypothalamus, Endocrinology 146, no. 10 (October 1, 2005): 4192–99.
154 «наблюдают за состоянием»: Ibid.
154 «резистентность к лептину и чрезмерная полнота»: X. Zhang, G. Zhang, H. Zhang, M. Karin, H. Bai, and D. Cai, Hypothalamic IKKbeta/NF- kappaB and ER Stress Link Overnutrition to Energy Imbalance and Obesity, Cell 135, no. 1 (October 3, 2008): 61–73.
154 «активность лептиновых рецепторов»: C. Bjørbæk, H. J. Lavery, S. H. Bates, R. K. Olson, S. M. Davis, J. S. Flier, et al., SOCS3 Mediates Feedback Inhibition of the Leptin Receptor via Tyr985, Journal of Biological Chemistry 275, no. 51 (December 22, 2000): 40649–57.
154 «фоне перекармливания»: Zhang, Zhang, Zhang, Karin, Bai, and Cai, Hypothalamic IKKbeta/NF- kappaB; H. Mori, R. Hanada, T. Hanada, D. Aki, R. Mashima, H. Nishinakamura, et al., Socs3 Defi ciency in the Brain Elevates Leptin Sensitivity and Confers Re sis tance to Diet- Induced Obesity, Nature Medicine 10, no. 7 (July 2004): 739–43.
155 «развилось ожирение»: J. P. Thaler, C.– X. Yi, E. A. Schur, S. J. Guyenet, B. H. Hwang, M. O. Dietrich, et al., Obesity Is Associated with Hypothalamic Injury in Rodents and Humans, Journal of Clinical Investigation 122, no. 1 (January 3, 2012): 153–62.